Neoatherosclerosis as reason for stent failures beyond 5 years after drug-eluting stent implantation

Neoatherosclerosis as reason for stent failures beyond 5 years after drug-eluting stent implantation.

Knaapen P, Nijveldt R, Heymans MW, Levi MM, van Rossum AC, Niessen HW, Marcu CB, Beek AM, van Royen N. Magnetic resonance imaging-defined areas of microvascular obstruction after acute myocardial infarction represent microvascular destruction and haemorrhage. Eur Heart J 2013;34:2346–2353. 28. Sezer M, Cimen A, Aslanger E, Elitok A, Umman B, Bugra Z, Yormaz E, Turkmen C, Adalet IS, Nisanci Y, U...

Neoatherosclerosis after Drug-Eluting Stent Implantation: Roles and Mechanisms

In-stent neoatherosclerosis (NA), characterized by a relatively thin fibrous cap and large volume of yellow-lipid accumulation after drug-eluting stents (DES) implantation, has attracted much attention owing to its close relationship with late complications, such as revascularization and late stent thrombosis (ST). Accumulating evidence has demonstrated that more than one-third of patients with...

Stent thrombosis after drug eluting stent implantation.

ince stent thrombosis (ST) is one of the serious and mortal complications after percutaneous coronary intervention (PCI), especially drug-eluting stent (DES) implantation, we are eager that the means of predicting and preventing ST be established. Several studies have reported an association between inflammation and stent thrombogenicity. In a clinical setting, Hwang et al1 reported a positive ...

Optical coherence tomographic analysis of in-stent neoatherosclerosis after drug-eluting stent implantation.

BACKGROUND We report findings from optical coherence tomography (OCT) of in-stent neoatherosclerosis as a cause of drug-eluting stent (DES) failure. METHODS AND RESULTS Optical coherence tomography and grayscale and virtual histology intravascular ultrasound were performed in 50 patients (30 stable, 20 unstable angina) with 50 DES in-stent restenosis lesions and intimal hyperplasia >50% of st...

drug-eluting stent fracture within 6 days after stent implantation